Cancer trial matching tool.

Helps clinicians identify clinical trials for patients on the basis of their genetic mutations.

Key Features


The Trial Matching Tool supports clinicians in the exploration of relevant experimental trial options for their patients. It answers questions such as “What clinical trial options are there for this patient based on their tumour genotype?”


The system ingests trials data from and applies natural language processing techniques to support precise matching based on genetic inclusion criteria. The tool supplements trial data with information from other sources regarding trial interventions and their mechanisms.


An instance is currently hosted at the link below to support matching to UK trials but the source code is available from GitHub and can be configured for other countries and sources of trial data. Data are refreshed daily and stored in an optimised way to support fast query performance.

Access the product

Cancer Trial Matching Tool website




Disclaimer: The digital health products created through UpSMART are for research use only as regulatory approval has not yet been sought. Please contact us if you wish to use any of the UpSMART products in a research study.


Digital Cancer Research team,

Cancer Research UK Manchester Institute

The University of Manchester

Wilmslow Road


M20 4BX